boronic acid derivative

By Targets:	Bacterial (1) Fluorescent Dye (1) Proteasome (1)
By Research Areas:	Infection (1) Inflammation/Immunology (1)

Targets Recommended: Amino Acid Derivatives Free Fatty Acid Receptor Fatty Acid Synthase (FASN) Apical Sodium-Dependent Bile Acid Transporter G protein-coupled Bile Acid Receptor 1

Cat. No.	Product Name	Target	Research Areas	Chemical Structure

HY-136072A

(1R,2S)-Xeruborbactam disodium

(1R,2S)-QPX7728 disodium
Others Others

(1R,2S)-Xeruborbactam ((1R,2S)-QPX7728) disodium is a boronic acid derivative .
HY-23524

HSL-IN-3

Others Others

HSL-IN-3 (example 42), a boronic acid ester derivative, is an inhibitor of hormone-sensitive lipase (HSL) .

(1R,2S)-Xeruborbactam disodium (1R,2S)-QPX7728 disodium	Others	Others
(1R,2S)-Xeruborbactam ((1R,2S)-QPX7728) disodium is a boronic acid derivative .

HSL-IN-3	Others	Others
HSL-IN-3 (example 42), a boronic acid ester derivative, is an inhibitor of hormone-sensitive lipase (HSL) .

HY-D1553

BODIPY-C12	Fluorescent Dye	Others
BODIPY-C12 is a boron-dipyrromethene derivative containing a lipophilic tail (excitation 490 nm). BODIPY-C12 is a hydrophobic molecular and sensitivity to the surrounding environment and can be used for quantify viscosity .

HY-142920

LMP7-IN-1	Proteasome	Inflammation/Immunology
LMP7-IN-1, a Boronic acid derivative, is a potent and selective immunoproteasome subunit LMP7 (β5i) inhibitor with an IC₅₀ of 1.83 nM (WO2021143923A1; compound 20) .

HY-150766

KPC-2-IN-1	Bacterial	Infection
KPC-2-IN-1, boronic acid derivative, is a potent KPC-2 inhibitor with K_i of 0.032 μM. KPC-2-IN-1 enhances the activity of cefotaxime in KPC-2 expressing E. coli. KPC-2-IN-1 exhibits well tolerated in human HEK-293 cells, which can be used for the study of E. coli resistance to β-lactam antibiotics .

Cat. No.	Product Name

HY-L167

Boronic Acid Compound Library	7 compounds
Boric acid is a stable and usually non-toxic group widely used in modern synthesis to form C-C and C-heteroatom bonds. Boric acid exhibits exquisite reversible coordination characteristics and can be explored as a molecular construction tool, with specific mechanisms for controlling the structure and biological characteristics of bioconjugates. Boric acid has various activities, such as anticancer, antibacterial, and antiviral activities. In drugs, boric acid mainly exists in the form of arylboronic acid. In addition to this form, heterocycles containing boric acid, such as pyridine, pyrrole, and indole derivatives, are also very useful in pharmaceutical chemistry. Molecular modification by introducing boric acid groups into bioactive molecules has been shown to alter selectivity, physicochemical, and pharmacokinetic characteristics, and improve existing activity. MCE designs a unique collection of 7 boronic acid compounds. It is a good tool to be used for research on cancer and other diseases.

Boronic Acid Compound Library

7 compounds

Boric acid is a stable and usually non-toxic group widely used in modern synthesis to form C-C and C-heteroatom bonds. Boric acid exhibits exquisite reversible coordination characteristics and can be explored as a molecular construction tool, with specific mechanisms for controlling the structure and biological characteristics of bioconjugates. Boric acid has various activities, such as anticancer, antibacterial, and antiviral activities. In drugs, boric acid mainly exists in the form of arylboronic acid. In addition to this form, heterocycles containing boric acid, such as pyridine, pyrrole, and indole derivatives, are also very useful in pharmaceutical chemistry. Molecular modification by introducing boric acid groups into bioactive molecules has been shown to alter selectivity, physicochemical, and pharmacokinetic characteristics, and improve existing activity.

MCE designs a unique collection of 7 boronic acid compounds. It is a good tool to be used for research on cancer and other diseases.

Cat. No.	Product Name	Type

HY-D1553

BODIPY-C12	Fluorescent Dyes/Probes
BODIPY-C12 is a boron-dipyrromethene derivative containing a lipophilic tail (excitation 490 nm). BODIPY-C12 is a hydrophobic molecular and sensitivity to the surrounding environment and can be used for quantify viscosity .

MCE Japan Authorized Agent ナミキ商事株式会社コスモ・バイオ株式会社
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Inhibitors & Agonists

Screening Libraries

Fluorescent Dye

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